Bioactivity:

Monomethyl auristatin E (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity.

CAS nr:

474645-27-7

Purity:

98%

Molecular Weight:

717,98

SMILES:

CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C

Formula:

C39H67N5O7

Pathway:

Cytoskeletal Signaling,Apoptosis

Target:

Microtubule Associated,Apoptosis