Bioactivity:

Lexibulin(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines). Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this may result in disruption of the tumor vascul

CAS nr:

917111-44-5

Purity:

98%

Molecular Weight:

434,53

SMILES:

c1(cccnc1)[C@@H](Nc1nc(ncc1C)c1ccc(c(c1)OC)NC(=O)NCC)CCC

Formula:

C24H30N6O2

Pathway:

Cytoskeletal Signaling,Metabolism,Immunology/Inflammation,NF-_b,Apoptosis

Target:

Microtubule Associated,Reactive Oxygen Species,Reactive Oxygen Species,Reactive Oxygen Species,Apoptosis