Bioactivity:

trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET) extracted from patent US20170121312A1 (Compound Example 129).

CAS nr:

2097132-93-7

Purity:

98%

Molecular Weight:

533,6

SMILES:

O=C([C@@]1(OC)CC[C@@H](C2=NC(NC3=NNC(C)=C3)=CC(C)=N2)CC1)N[C@H](C4=CC=C(N5N=CC(F)=C5)N=C4)C

Formula:

C27H32FN9O2

Pathway:

Tyrosine Kinase/Adaptors,Apoptosis

Target:

c-RET,c-RET