AKB-6899 T29797
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
AKB-6899 leads to stabilization of HIF-2_ which induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model.
CAS nr:
1007377-55-0
Purity:
98%
Molecular Weight:
290,25
SMILES:
O=C(O)CNC(C1=NC=C(C2=CC=CC(F)=C2)C=C1O)=O
Formula:
C14H11FN2O4
Pathway:
Metabolism,Chromatin/Epigenetic,Angiogenesis,Tyrosine Kinase/Adaptors,Chromatin/Epigenetic,Angiogenesis
Target:
HIF/HIF Prolyl-Hydroxylase,HIF/HIF Prolyl-Hydroxylase,VEGFR,VEGFR,HIF,HIF
