Bioactivity:

Selpercatinib is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively)

CAS nr:

2152628-33-4

Purity:

98%

Molecular Weight:

525,6

SMILES:

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

Formula:

C29H31N7O3

Pathway:

Tyrosine Kinase/Adaptors,Apoptosis

Target:

c-RET,c-RET