Bioactivity:

Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)

CAS nr:

1800070-77-2

Purity:

98%

Molecular Weight:

596,68

SMILES:

C=CC(=O)NC1=CC2=C(C=C1)NC(=O)N2C3CCN(CC3)CC4=CC=C(C=C4)C5=C(C=C6C(=N5)C=CNC6=O)C7=CC=CC=C7

Formula:

C36H32N6O3

Pathway:

Cytoskeletal Signaling,PI3K/Akt/mTOR signaling

Target:

Akt,Akt