Bioactivity:

Dihydrocucurbitacin B has anti-cancer activity, it reduces cell proliferation due to a decrease in the expression of cyclins, mainly cyclin-B1 and disruption of the actin cytoskeleton, arresting B16F10 cells in G2/M phase.

CAS nr:

13201-14-4

Purity:

98%

Molecular Weight:

560,7

SMILES:

[H][C@@]12C[C@H](O)C(=O)C(C)(C)C1=CC[C@@]1([H])[C@]3(C)C[C@@H](O)[C@H]([C@@](C)(O)C(=O)CCC(C)(C)OC(C)=O)[C@@]3(C)CC(=O)[C@@]21C

Formula:

C32H48O8

Pathway:

Immunology/Inflammation,Apoptosis,Neuroscience,Immunology/Inflammation

Target:

IL Receptor,TNF,COX,COX