MD-224 T11980
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
MD-224 is a highly potent and efficacious MDM2 degrader based on the proteolysistargeting chimera (PROTAC) concept,and as a new class of anticancer agent.
CAS nr:
2136247-12-4
Purity:
98%
Molecular Weight:
889,8
SMILES:
Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCCCC2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)Nc1ccc(cc1)C(=O)NCCCC#Cc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O
Formula:
C48H43Cl2FN6O6
Pathway:
Apoptosis,Ubiquitination
Target:
Mdm2,E1/E2/E3 Enzyme
