Bioactivity:

AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively.

CAS nr:

1011531-27-3

Purity:

98%

Molecular Weight:

488,48

SMILES:

OC(C[C@H](C1=NOC=C1)C(C=C2)=CC=C2OCC(S3)=C(C)N=C3C4=CC=C(C(F)(F)F)C=C4)=O

Formula:

C24H19F3N2O4S

Pathway:

Endocrinology/Hormones,GPCR/G Protein

Target:

GPR,GPR