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Cabozantinib hydrochloride T5164

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).

CAS nr:

T5164

Purity:

98%

Molecular Weight:

537,96

SMILES:

Cl.COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC

Formula:

C28H25ClFN3O5

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Metabolism,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors

Target:

FLT,FLT,VEGFR,VEGFR,TAM Receptor,ROR,c-Kit,c-Met/HGFR