Semagacestat T6125
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Semagacestat (LY450139) is a _-secretase blocker for A_42/A_40/A_38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).
CAS nr:
425386-60-3
Purity:
98%
Molecular Weight:
361,44
SMILES:
C[C@@H](C(=O)N[C@H]1c2ccccc2CCN(C1=O)C)NC(=O)[C@H](C(C)C)O
Formula:
C19H27N3O4
Pathway:
Stem Cells,Proteases/Proteasome,Neuroscience,Neuroscience
Target:
Gamma-secretase,Gamma-secretase,Gamma-secretase,Beta Amyloid
