Bioactivity:

LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, DNA-PK, and mTOR. LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.

CAS nr:

1386874-06-1

Purity:

98%

Molecular Weight:

406,48

SMILES:

O=c1n(c2c(c3cc(c4cc(C(O)(C)C)cnc4)ccc3nc2)n1C[C@H](C)OC)C

Formula:

C23H26N4O3

Pathway:

PI3K/Akt/mTOR signaling,PI3K/Akt/mTOR signaling,Autophagy,PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair

Target:

mTOR,PI3K,Autophagy,DNA-PK,DNA-PK