Bioactivity:

PS210 is inactive against other protein kinases, including PDK1 downstream signaling components such as S6K, PKB/Akt, or GSK3. PS210 is a potent and selective PDK1 activator (Kd: 3 _M) and targets the PIF-binding pocket of PDK1. In cells, the prodrug of P

CAS nr:

1221962-86-2

Purity:

98%

Molecular Weight:

380,31

SMILES:

C1=CC=C(C=C1)C(CC(=O)C2=CC=C(C=C2)C(F)(F)F)C(C(=O)O)C(=O)O

Formula:

C19H15F3O5

Pathway:

PI3K/Akt/mTOR signaling

Target:

PDK