Bioactivity:

Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.

CAS nr:

1394820-77-9

Purity:

98%

Molecular Weight:

728,79

SMILES:

O=C(C1=C(C)N(C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(OC4=CC=NC5=CC(OCC(C)(O)C)=CC=C45)C(F)=C3.CC6=CC=C(S(=O)(O)=O)C=C6

Formula:

C38H37FN4O8S

Pathway:

Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors

Target:

c-Met/HGFR,VEGFR,VEGFR,TAM Receptor