Leptomycin B T15735
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Leptomycin B is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue.
CAS nr:
87081-35-4
Purity:
98%
Molecular Weight:
540,73
SMILES:
CC/C(/C=C/[C@@H]([C@@H](C)C=C1)OC1=O)=C/[C@H](C)C/C=C/C(/C)=C/[C@@H](C)C([C@@H](C)[C@@H]([C@@H](C)C/C(/C)=C/C(O)=O)O)=O
Formula:
C33H48O6
Pathway:
Microbiology/Virology,Microbiology/Virology,Membrane transporter/Ion channel
Target:
Antifungal,Antibiotic,CRM1
