Bioactivity:

Radicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: 1 _M). Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients,

CAS nr:

12772-57-5

Purity:

98%

Molecular Weight:

364,78

SMILES:

OC1=C2C(CC(/C=C/C=C\[C@@H](O3)[C@H]3C[C@@H](C)OC2=O)=O)=C(Cl)C(O)=C1

Formula:

C18H17ClO6

Pathway:

Metabolism,Cytoskeletal Signaling

Target:

HSP,HSP