Palbociclib-propargyl T18515
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Palbociclib-propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP-10. CP-10 shows a DC50 of 2.1 nM for CDK6[1].
CAS nr:
2366269-23-8
Purity:
98%
Molecular Weight:
485,58
SMILES:
O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCN(CC#C)CC4)C=C3)N=C2N1C5CCCC5
Formula:
C27H31N7O2
Pathway:
Others
Target:
Others
