Bioactivity:

NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.

CAS nr:

113104-25-9

Purity:

98%

Molecular Weight:

290,25

SMILES:

[O-][N+](=O)c1ccc(Sc2cccc[n+]2[O-])c2nonc12

Formula:

C11H6N4O4S

Pathway:

Chromatin/Epigenetic,Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors,DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Chromatin/Epigenetic

Target:

Epigenetic Reader Domain,EGFR,EGFR,EGFR,DNA/RNA Synthesis,DNA/RNA Synthesis,Histone Acetyltransferase