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Bioactivity:
K-Ras-PDE_-IN-1 is a potent inhibitor of competitive K-Ras-PDE_.It binds to the farnesyl binding pocket of PDE_(Kd of 8 nM).
CAS nr:
1841464-21-8
Purity:
98%
Molecular Weight:
447,5
SMILES:
Cc1ccc(cc1)-n1cc2c(C)nn(CCCC(=O)NCCc3ccc(F)cc3)c(=O)c2n1
Formula:
C25H26FN5O2
Pathway:
Metabolism
Target:
PDE