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Bioactivity:
GSK319347A is a TBK1 and IKK_ dual inhibitor (IC50s: 93 nM and 469 nM, respectively). GSK319347A inhibits IKK2 (IC50: 790 nM).
CAS nr:
862812-98-4
Purity:
98%
Molecular Weight:
469,53
SMILES:
COC1=CC2=C(C=C1OC)N(C3=CC(OCC4=CC=CC=C4S(=O)(C)=O)=C(C#N)S3)C=N2
Formula:
C22H19N3O5S2
Pathway:
NF-_b
Target:
I_B/IKK