Bioactivity:

Rapamycin, a macrolide compound obtained from Streptomyces hygroscopicus, is a potent and specific mTOR inhibitor (IC50: 0.1 nM in HEK293 cells).

CAS nr:

53123-88-9

Purity:

98%

Molecular Weight:

914,18

SMILES:

CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O

Formula:

C51H79NO13

Pathway:

PI3K/Akt/mTOR signaling,Metabolism,Microbiology/Virology,Microbiology/Virology,Others,Autophagy

Target:

mTOR,Endogenous Metabolite,Antifungal,Antibiotic,Others,Autophagy