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Bioactivity:
KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633 for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.
CAS nr:
286370-15-8
Purity:
98%
Molecular Weight:
416,86
SMILES:
CCCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1Cl
Formula:
C20H21ClN4O4
Pathway:
Tyrosine Kinase/Adaptors,Angiogenesis
Target:
VEGFR,VEGFR