Bioactivity:

Beta-Hydroxyisovalerylshikonin is an ATP non-competitive inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines.

CAS nr:

7415-78-3

Purity:

Molecular Weight:

388,42

SMILES:

CC(C)(CC(O[C@H](CC=C(C)C)C(C(c1c2c(O)ccc1O)=O)=CC2=O)=O)O

Formula:

C21H24O7

Pathway:

PI3K/Akt/mTOR signaling,GPCR/G Protein,Immunology/Inflammation,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors,Metabolism

Target:

AMPK,Prostaglandin Receptor,Prostaglandin Receptor,Src,Src,EGFR,EGFR,EGFR,Tyrosine Kinases,Fatty Acid Synthase