Bioactivity:

Shikonin is an TMEM16A chloride channel inhibitor (IC50: 6.5 _M). Shikonin is also a selective PKM2 inhibitor and can also suppress activation of the NF-_B pathway and inhibit TNF-_. Shikonin decreases exosome secretion through the inhibition of glycolysi

CAS nr:

517-89-5

Purity:

98%

Molecular Weight:

288,3

SMILES:

C\C(C)=C\C[C@@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O

Formula:

C16H16O5

Pathway:

Membrane transporter/Ion channel,Apoptosis,Proteases/Proteasome,Microbiology/Virology,NF-_b,Metabolism

Target:

Chloride channel,TNF,HIV Protease,HIV Protease,NF-_B,PKM