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Bioactivity:
ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-_ from cell membranes.
CAS nr:
689284-12-6
Purity:
98%
Molecular Weight:
415,54
SMILES:
Formula:
C19H37N5O5
Pathway:
Target: