TargetMol Chemicals

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TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

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Nutlin-3 T2158

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

Nutlin-3 is an MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50: 0.09 _M) and activates p53. Antiproliferative agent; chemotherapeutic agent; induces apoptosis in Y cells.

CAS nr:

548472-68-0

Purity:

98%

Molecular Weight:

581,49

SMILES:

COc1ccc(C2=NC(C(N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1

Formula:

C30H30Cl2N4O4

Pathway:

Ubiquitination

Target:

E1/E2/E3 Enzyme