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Bioactivity:
GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
CAS nr:
1168091-68-6
Purity:
98%
Molecular Weight:
456,21
SMILES:
OCCONC(=O)c1ccc2cncn2c1Nc1ccc(I)cc1F
Formula:
C16H14FIN4O3
Pathway:
MAPK,Apoptosis
Target:
MEK,Apoptosis