Bioactivity:

KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3_( IC50s of 19 and 10 nM, respectively). It�activates Wnt/_-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3_ activity.�KY19382 can be used for th

CAS nr:

2226664-93-1

Purity:

98%

Molecular Weight:

360,2

SMILES:

CO/N=C\1/C2=CC=CC=C2N=C1C3=C(NC4=CC(=C(C=C43)Cl)Cl)O

Formula:

C17H11Cl2N3O2

Pathway:

Stem Cells,Cytoskeletal Signaling,Others,Stem Cells,PI3K/Akt/mTOR signaling

Target:

Wnt/beta-catenin,Wnt/beta-catenin,Others,GSK-3,GSK-3