Bioactivity:

TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively).

CAS nr:

2097262-58-1

Purity:

98%

Molecular Weight:

468,47

SMILES:

CC1=C(C=C(C(C)=C1)C(N2CC(C2)C3=CC=C(C=C3)C#N)=O)C4=C(N=C(N4)C(F)(F)F)COC

Formula:

C25H23F3N4O2

Pathway:

Metabolism

Target:

Fatty Acid Synthase