Bioactivity:

1. Talatisamine (12 _M) and TEA (5mM) inhibits the enhanced I(K) caused by A_4 oligomers, attenuates cytotoxicity of A_ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talatisamine can therefore be considered

CAS nr:

20501-56-8

Purity:

98%

Molecular Weight:

421,57

SMILES:

CCN1C[C@]2(COC)CC[C@H](OC)[C@@]34[C@@H]5C[C@H]6[C@H](O)[C@@H]5[C@](O)(C[C@@H]6OC)[C@@H](C[C@H]23)C14

Formula:

C24H39NO5

Pathway:

Membrane transporter/Ion channel

Target:

Potassium Channel