DK419 T15137
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
DK419 is an orally active inhibitor of Wnt/_-catenin signaling (IC50: 0.19 _M). DK419 decreases protein levels of Axin2, _-catenin, c-Myc, Cyclin D1, and Survivin. It also induces the production of pAMPK.
CAS nr:
2102672-22-8
Purity:
98%
Molecular Weight:
407,7
SMILES:
O=C(C1=C2C(N=C(C(F)(F)F)N2)=CC(Cl)=C1)NC3=CC=C(C(F)(F)F)C=C3
Formula:
C16H8ClF6N3O
Pathway:
Stem Cells,Cytoskeletal Signaling
Target:
Wnt/beta-catenin,Wnt/beta-catenin
