Bioactivity:

Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.

CAS nr:

1196070-26-4

Purity:

98%

Molecular Weight:

659,81

SMILES:

CC(C([O-])=O)(C)CC1=C(SC(C)(C)C)C2=CC(OCC3=CC=C(C)C=N3)=CC=C2N1CC4=CC=C(C5=CN=C(OCC)C=C5)C=C4.[Na+]

Formula:

C38H42N3NaO4S

Pathway:

Immunology/Inflammation

Target:

LTR