Bioactivity:

APG-115 (AA-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively[1]. APG-115 blocks the interaction of MDM2 and p53. And it induces cell-cycle arrest and apoptosis in a p53-depend

CAS nr:

1818393-16-6

Purity:

98%

Molecular Weight:

642,59

SMILES:

O=C1NC2=CC(Cl)=CC=C2[C@]13C4(CCCCC4)N(CC)[C@@H](C(NC56CCC(CC6)(C(O)=O)CC5)=O)[C@@H]3C7=C(C(Cl)=CC=C7)F

Formula:

C34H38Cl2FN3O4

Pathway:

Others

Target:

Others