Bioactivity:

MRT00033659 is an effective broad-spectrum kinase inhibitor of CK1 (IC50=0.9 ﾵM for CK1_) and CHK1 (IC50=0.23 ﾵM). MRT00033659 is a pyrazolo-pyridine analogue. It also induces p53 pathway activation and E2F-1 destabilization.

CAS nr:

1401731-54-1

Purity:

98%

Molecular Weight:

266,3

SMILES:

CC1=NNC2=NC=C(C=C21)C3=CC=CC(NC(C)=O)=C3

Formula:

C15H14N4O

Pathway:

Others

Target:

Others