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Altiratinib T2054

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

Altiratinib(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with an HGF antagonist in vitro.

CAS nr:

1345847-93-9

Purity:

98%

Molecular Weight:

510,46

SMILES:

FC1=CC=C(NC(=O)C2(CC2)C(=O)NC2=CC(F)=C(OC3=CC(NC(=O)C4CC4)=NC=C3)C=C2F)C=C1

Formula:

C26H21F3N4O4

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors

Target:

FLT,FLT,VEGFR,VEGFR,Tie-2,Trk receptor,c-Met/HGFR