Bioactivity:

Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction. Isosilybin B showed inhibito

CAS nr:

142796-22-3

Purity:

98%

Molecular Weight:

482,4

SMILES:

COc(cc([C@@H]1Oc(ccc([C@H]([C@H](C2=O)O)Oc3c2c(O)cc(O)c3)c2)c2O[C@H]1CO)cc1)c1O

Formula:

C25H22O10

Pathway:

PI3K/Akt/mTOR signaling,Apoptosis,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling

Target:

PI3K,Mdm2,Akt,Akt