Bioactivity:

OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor (IC50: 2.7 _M).

CAS nr:

1681056-61-0

Purity:

98%

Molecular Weight:

563,64

SMILES:

O=C(N(CC1=CC=CS1)CC2=CC=CO2)[C@H](NS(C3=CC(C=C4)=C(C=C3)NC4=O)(=O)=O)C5=CC=CC=C5OC

Formula:

C28H25N3O6S2

Pathway:

Proteases/Proteasome,Metabolism,Others

Target:

Acyltransferase,Acyltransferase,Others