Bioactivity:

Danicopan (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may b

CAS nr:

1903768-17-1

Purity:

98%

Molecular Weight:

580,41

SMILES:

CC1=NC=C(C=N1)C2=CC3=C(C=C2)N(N=C3C(=O)C)CC(=O)N4C[C@@H](C[C@H]4C(=O)NC5=NC(=CC=C5)Br)F

Formula:

C26H23BrFN7O3

Pathway:

Immunology/Inflammation

Target:

Complement System