Bioactivity:

Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expression.

CAS nr:

37239-48-8

Purity:

98%

Molecular Weight:

873,8

SMILES:

C[C@](COC(c1c(CC[C@](C)(C(O[C@@H]([C@@H]2OC(c3cocc3)=O)[C@]3(C)O)=O)O)nccc1)=O)([C@@H]([C@H]1OC(C)=O)[C@H]([C@H]4OC(C)=O)OC(C)=O)O[C@]13[C@@]4(COC(C)=O)[C@H]2OC(C)=O

Formula:

C41H47NO20

Pathway:

Apoptosis

Target:

BCL