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Bioactivity:
(+)-JQ1 is a BET bromodomain inhibitor (IC50: 77 nM/33 nM for BRD4 (1/2)).
CAS nr:
1268524-70-4
Purity:
98%
Molecular Weight:
456,99
SMILES:
Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)OC(C)(C)C)c1nnc(C)n-21)c1ccc(Cl)cc1
Formula:
C23H25ClN4O2S
Pathway:
Chromatin/Epigenetic,Autophagy
Target:
Epigenetic Reader Domain,Autophagy