Bioactivity:

MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits cytotoxicity against human lung CL1

CAS nr:

1417997-93-3

Purity:

98%

Molecular Weight:

345,39

SMILES:

COc1cc(c(/C=C/C(=O)NO)cc1)c2ccc(cc2)c3ccccc3

Formula:

C22H19NO3

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic

Target:

HDAC,HDAC