Bioactivity:

JWG-071 is the first reported kinase-selective chemical probe for ERK5. JWG-071 will be a much-needed chemical probe for deconvoluting ERK5 and BRD4 pharmacology[1]. JWG-071 improves ERK5 activity and BRD4 selectivity.

CAS nr:

2250323-50-1

Purity:

98%

Molecular Weight:

612,76

SMILES:

COC1=CC(C(N2CCC(N3CCN(C)CC3)CC2)=O)=CC=C1NC4=NC=C(N(C)C5=O)C(N(C6=CC=CC=C65)C(C)CC)=N4

Formula:

C34H44N8O3

Pathway:

MAPK

Target:

ERK