Bioactivity:

BRD0639 is a potent PRMT5 inhibitor. BRD0639 engages the target in cells, disrupts PRMT5-RIOK1 complexes, and reduces substrate methylation. BRD0639 is a first-in-class PBM-competitive inhibitor that can support studies of PBM-dependent PRMT5 activities a

CAS nr:

T9329

Purity:

98%

Molecular Weight:

SMILES:

Formula:

Pathway:

Chromatin/Epigenetic

Target:

Histone Methyltransferase