Bioactivity:

L-161982 is a selective EP4 receptor antagonist. L-161982 decreases collagen-induced arthritis in mice. L-161982 fully blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells.

CAS nr:

147776-06-5

Purity:

98%

Molecular Weight:

654,72

SMILES:

O=C(C1=C(C)C=CS1)NS(=O)(C2=CC=CC=C2C3=CC=C(CN4C(CCCC)=NN(C5=CC=CC=C5C(F)(F)F)C4=O)C=C3)=O

Formula:

C32H29F3N4O4S2

Pathway:

GPCR/G Protein,Immunology/Inflammation

Target:

Prostaglandin Receptor,Prostaglandin Receptor