Bioactivity:

Samuraciclib hydrochloride is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold higher than CDK1, CDK2 (IC50 is 578 nM), CDK5 and CDK9 respe

CAS nr:

1805789-54-1

Purity:

98%

Molecular Weight:

430,97

SMILES:

CC(C)C1=C2N=C(C=C(N2N=C1)NCC3=CC=CC=C3)NC[C@H]4CCNC[C@@H]4O.Cl

Formula:

C22H31ClN6O

Pathway:

Cell Cycle/Checkpoint,Apoptosis

Target:

CDK,Apoptosis