Bioactivity:

TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating.�TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM

CAS nr:

953778-63-7

Purity:

98%

Molecular Weight:

378,4

SMILES:

C[C@H](C1=NC=C(C=C1)OCC(F)(F)F)NC(=O)CC2=CC=C(C=C2)C3CC3

Formula:

C20H21F3N2O2

Pathway:

Metabolism,Membrane transporter/Ion channel

Target:

Calcium Channel,Calcium Channel