Bioactivity:

SNS-032 is a selective inhibitor of CDK2 (IC50: 48 nM ) and is 10- and 20-fold selective over CDK1/CDK4. It is also sensitive to CDK7/9 (IC50: 62 nM/4 nM), and no effect on CDK6.

CAS nr:

345627-80-7

Purity:

98%

Molecular Weight:

380,53

SMILES:

CC(C)(C)c1cnc(o1)CSc1cnc(s1)NC(=O)C1CCNCC1

Formula:

C17H24N4O2S2

Pathway:

Cell Cycle/Checkpoint,Stem Cells,PI3K/Akt/mTOR signaling,Apoptosis

Target:

CDK,GSK-3,GSK-3,Apoptosis