Bioactivity:

TP-064 is a potent and selective PRMT4 inhibitor. TP-064 includes inhibition of PRMT4 with IC50 < 10nM for methylation of H3 (1-25) and greater than 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. TP-064 inhibits the

CAS nr:

2080306-20-1

Purity:

98%

Molecular Weight:

458,61

SMILES:

O=C(N(C)CC1=CC(C2CCN(CCNC)CC2)=NC=C1)C3=CC=CC(OC4=CC=CC=C4)=C3

Formula:

C28H34N4O2

Pathway:

Chromatin/Epigenetic

Target:

Histone Methyltransferase