Bioactivity:

MRT199665 is an effective and ATP-competitive, selective MARK/SIK/AMPK inhibitor (IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPK_1/AMPK_2, and SIK1/SIK2/SIK3, respectively). MRT199665 suppresses the phosphorylation of S

CAS nr:

1456858-57-3

Purity:

98%

Molecular Weight:

469,58

SMILES:

O=C1C(C)(C)C2=CN=C(NC3=CC=CC(CN4CCCC4)=C3)N=C2N1[C@H]5CCC6=C5C=CC=C6O

Formula:

C28H31N5O2

Pathway:

Others

Target:

Others