Bioactivity:

YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 _M for inhibiting GRP78 ATPase activity of the full-length protein).�It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.

CAS nr:

423145-35-1

Purity:

98%

Molecular Weight:

398,84

SMILES:

O=C(CCC)NC(C1=CC=C2C(OCO2)=C1)C(C=C(Cl)C3=C4N=CC=C3)=C4O

Formula:

C21H19ClN2O4

Pathway:

Metabolism,Cytoskeletal Signaling,Endocrinology/Hormones,GPCR/G Protein,Apoptosis

Target:

HSP,HSP,GPR,GPR,Apoptosis